Studies reveal: Anti-aging pills fail to deliver results
Trust no pill to deliver that much elusive 'fountain of youth' – apparently, or at least not yet.
DHEA supplements, marketed as rejuvenating agents and testosterone patches were touted anti-aging treatments. But in one of the first careful studies to test such claims in older men and women, these widely used substances failed to improve the participants' strength, their physical performance, and their body's ability to lower levels of blood sugar, or certain other measures of health.
A Dutch study last year found no benefit of DHEA in 100 men 70 and older. With new tests undertaken, the scientists are now doubtful if the substances actually help older people.
A new study, published in New England Journal of Medicine was initiated by researchers at the Mayo Clinic in Minnesota and the University of Padua in Italy. Participants were examined for any changes in body fat, hormone levels, bone density, and performance on treadmill, weightlifting and leg flexibility tests. The men and women also filled out questionnaires about how they felt and their quality of life.
Lead author of the study, Dr. K. Sreekumaran Nair was quoted, saying: "I don't think there's any case for administering these to elderly people."
In an accompanying editorial, Dr. Paul Stewart of England's University of Birmingham have said that more research should be done on DHEA, and if it proves safe and effective, it should be regulated as a drug. "Without a reversal of the current U.S. legislation, DHEA is likely to continue to be used inappropriately, and quackery will prevail," Stewart wrote.
Nonetheless, "No harmful side effects were detected…that is good news, but it does not mean the supplements are altogether safe,” noted Simon Yeung, manager of the Web site on supplements and integrative medicine at the Memorial Sloan-Kettering Cancer Center in New York.
DHEA, a steroid, is a precursor to the sex hormones testosterone and estrogen, is made by the body, but levels decline rapidly after age 25. Testosterone is available by prescription only. But the Food and Drug Administration classifies DHEA as a supplement, meaning it can be sold without meeting the same safety and effectiveness standards as a drug.

